Inseal Medical Ltd. develops and manufactures percutaneous vascular closure devices for sealing of puncture sites following treatment involving a large bore sheath. The Company’s first product is the InSeal intravascular closure device, which supports the closure of 14-21Fr punctures in vessels of 6-10mm in diameter.

InSeal’s fully percutaneous vascular closure device (VCD) is made of a self expandable Nitinol frame covered with a biodegradable membrane. The InSeal VCD is delivered using the same sheath utilized for the large bore procedure, e.g. transcatheter aortic valve replacement (TAVR) or endo-vascular aneurysm repair (EVAR). The InSeal VCD is deployed across the access puncture, with the biodegradable membrane covering the puncture and exploiting blood pressure to assure its sealing against the vessel wall. The delivery and deployment of the InSeal VCD is simple and takes less than 2 minutes to complete.

View InSeal animation video highlighting key steps of the procedure.

InSeal Medical Ltd. is a fully owned subsidiary of E-Pacing Inc. and is backed by Polaris Venture Partners (Waltham, MA).

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